近来发现了NCBI的E-utilities软件，不可思议的程序。实现自动化的大批量的从Entrez数据库下载数据。并且提供了几种常用的语言以供选择，像Perl, Python, Java, 和 C++等。真是太强大了。也挺复杂的。先收藏教程，再慢慢学习吧。
E-utilities:automate search and retrieval operations across the entire suite of Entrez databases.

Course Objectives
During the course, participants will learn how to do the following:

• Post E-utility calls using standard URLs in Perl and using SOAP in Visual C#
• Design and execute complex searches across the 35 Entrez databases
• Implement data pipelines for genomic, proteomic, or microarray analysis
• Create automated searches to keep local databases current
• Create and download customized datasets
• Seamlessly combine local data with NCBI data
• Develop a focused interface to NCBI data

教程一：http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=coursework&part=eutils

教程二：http://www.ncbi.nlm.nih.gov/Class/PowerTools/eutils/schedule.html

Course Schedule：

最新的说明文档:http://eutils.ncbi.nlm.nih.gov/entrez/query/static/eutils_help.html