1,SMART入门,蛋白结构和功能分析
详细: http://www.liucheng.name/?p=738
2,Sanger的Pfam数据库
目前的版本:Pfam 23.0 (July 2008, 10340 families)
The Pfam database is a large collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs).
3,NCBI的CDD(Conserved Domain Database)数据库
网址:http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi
Proteins often contain several modules or domains, each with a distinct evolutionary origin and function. NCBI's Conserved Domain Database is a collection of multiple sequence alignments for ancient domains and full-length proteins.
最后,自己试验一下。上面两个图的结果的数据是用了NP_776850的蛋白序列。你也可以拿这个序列来运行一下看看。
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