三种分析蛋白结构域(Domains)的方法

1，SMART入门，蛋白结构和功能分析

详细: http://www.liucheng.name/?p=738

2，Sanger的Pfam数据库

网址：http://pfam.sanger.ac.uk/

目前的版本：Pfam 23.0 (July 2008, 10340 families)

The Pfam database is a large collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs).

3，NCBI的CDD（Conserved Domain Database）数据库

网址：http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi

Proteins often contain several modules or domains, each with a distinct evolutionary origin and function. NCBI’s Conserved Domain Database is a collection of multiple sequence alignments for ancient domains and full-length proteins.

最后，自己试验一下。上面两个图的结果的数据是用了NP_776850的蛋白序列。你也可以拿这个序列来运行一下看看。